Microbiology

Charles River conducts a wide range of efficacy studies for animal health products to determine antimicrobial activity. We conduct studies to assess the effects of antimicrobial residues on human gut flora, including in vitro model systems designed to monitor the potential for the development of resistance. We also conduct sterility, preservative efficacy and microbial limit testing, often working to client protocols.

Our experienced microbiologists offer bacteriology services to investigate the effect of animal feed additives on the shedding of zoonotic organisms, such as Salmonella spp. and Campylobacter, by food-producing animals.

As a result of the increasing concern worldwide regarding the spread of antibiotic resistance in bacteria, we offer a full monitoring service including collection and maintenance of zoonotic organisms and bacteria as well as data analysis, as required by the governing regulatory authorities.

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Target Animal Safety Studies

Our experience covers a diverse range of product types, and the related studies are fully supported in-house with clinical chemistry, veterinary pathology and statistical services.

Analytical Support

Charles River offers a comprehensive analytical service to support residue and pharmacokinetic investigations.

Toxicology Studies

Leading the industry in the fields of reproductive toxicology, inhalation, infusion, bone research and other specialty toxicological assessments.

Veterinary Field Studies

As well as efficacy and safety, we can conduct certain dose confirmation and post-marketing studies in the field. Treatment routes have included injectables, intramammaries, water medications, oral dosing and in-feed medications.