Inhalation Toxicology

Utilizing knowledge from decades of experience in the field, Charles River offers a full range of inhalation toxicology study designs to support the worldwide registration of biocides. In modern laboratory facilities with custom-designed apparatus, we conduct a variety of study designs in multiple species.

Study Types

  • Acute toxicity
  • Subacute to chronic
  • Reproduction and teratogenicity
  • Neurotoxicology
  • ADME/TK
  • Dry powders
  • Aerosols
  • Emulsion sprays
  • Vapors
  • Gases
  • Compound-specific methodologies can be developed and validated.
  • Sorbent tubes or impingers are used to sample test atmospheres.
  • Chemical or gravimetric assessment of test atmospheres
  • Online infrared or GC analysis for gases and vapors
  • Real-time aerosol monitors (RAM-S) for measuring particulates
  • Aerosol particle size distribution monitored using cascade impactors or laser optical systems

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Ecotoxicology Studies

Our custom-designed ecotoxicology facility is equipped to run aquatic and terrestrial ecotoxicology investigations.

5-Batch Analysis

Charles River has been conducting these tests since 1990, carrying out many successful programs involving various pesticide classes, including insecticides, herbicides, fungicides and biocides.

Skin Penetration Studies

Charles River performs in vitro skin penetration studies with human skin in support of biocide development.