Metabolism Studies

Charles River has over 30 years of experience performing rodent and livestock metabolism studies that meet international regulatory standards for biocide development.

Our scientists offer a comprehensive and integrated service for the profiling and identification of metabolites in excreta, milk, eggs and tissues. Modern chromatographic and isolation technologies are supported by Micromass
Q-ToF and IT-ToF mass spectrometers and access to NMR for definitive metabolite identification. We can also provide metabolite reference standards for future structural confirmation.

  • Lactating cattle
  • Lactating goats
  • Pigs (including neonatal and minipigs)
  • Rodents
  • Poultry
  • Dermal
  • Oral (diet, capsule or gavage)
  • Intravenous
  • Inhalation

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Physicochemical Characterization

We offer a full range of physicochemical testing to meet all regulatory requirements, either as full testing programs or stand-alone tests.

Toxicology Studies

Leading the industry in the fields of reproductive toxicology, inhalation, infusion, bone research and other specialty toxicological assessments.

Residue Analysis

Using samples from studies conducted at Charles River, or provided by you, we can develop assays or evaluate and modify a supplied method using a full suite of analytical techniques and instrumentation.