Developed by C.C. Little in 1921, from a mating of Miss Abby Lathrop’s stock that also gave rise to strains C57BR and C57L. Strains 6 and 10 separated about 1937. To The Jackson Laboratory in 1948 from Hall. To NIH in 1951 from The Jackson Laboratory at F32. To Charles River in 1974 from NIH.

Coat Color


MHC Haplotype


Ideal For:

General multipurpose model, diet-induced obesity, transgenic/knockout model development, safety and efficacy testing, immunology

Strain Code:


Informational Resources: C57BL/6 Mouse

Control Data

Diet Information for Enhancing or Expressing a Desired Disease Condition:

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Preconditioned Models

We offer services that include pre-identification, pre-screening, pre-dosing/pre-injection, feeding, aging and phenotypic evaluations.


We provide biospecimens, including blood products, tissues and organs, for use in better understanding your compound’s pharmacokinetic properties.