Developed from the transfer of the nude gene from Crl:NU-Foxn1nu to a CD-1® mouse through a series of crosses and backcrosses beginning in 1979 at Charles River Laboratories, Wilmington, MA. The animal lacks a thymus, is unable to produce T-cells, and is therefore immunodeficient.
Hairless, albino background
Tumor biology and xenograft research
086 (Homozygous), 087 (Heterozygous, not immunodeficient)
Informational Resources: CD-1® Nude Mouse
CD-1 Nude Mouse Health Reports
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Health Reports for Animal Colonies in Germany
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Health Reports for Animal Colonies in UK
Health Reports for Animal Colonies in Italy
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