Origin

Originated in 1925 by Robert W. Dawley from a hybrid hooded male and a female Wistar rat. To Charles River in 1950 from Sprague Dawley, Inc. In 1991, 8 colonies were selected to form the IGS Foundation Colony. Rederived into an isolator foundation colony in 1997. IGS refers to animals bred using the Charles River International Genetic Standardization (IGS) Program.

Coat Color

White (albino)

Ideal For:

General multipurpose model, safety and efficacy testing, aging, nutrition, diet-induced obesity, oncology, surgical model

Strain Code:

001

Informational Resources: CD® Rat

• CD IGS Rat Model Information Sheet
• International Genetic Standardization (IGS) Program

Technical Data

• Compilation of Spontaneous Neoplastic Lesions and Survival in Crl:CD(SD) Rats From Control Groups - March 2013
• Histopathology Findings in 4-26 Week Old Crl:CD(SD) Rats - March 2012
• Clinical Laboratory Parameters for Crl:CD(SD) Rats - March 2006
• Compilation of Spontaneous Neoplastic Lesions and Survival in Crl:CD(SD) Rats from Control Group - March 2004
• Postnatal Growth, Development, and Behavioral/Functional Evaluation Crl:CD (SD)IGS BR Rats - March 2002
• Compilation of Spontaneous Neoplastic Lesions and Survival in Crl:CD® (SD) BR Rats from Control Groups - March 2001
• The Development and Maintenance of the Crl:CD®(SD)IGS BR Rat Breeding System - 1998
• Spontaneous Neoplastic Lesions and Survival in Crl:CD®(SD)BR Rats Maintained on Dietary Restriction - March 1998
• Historical Control Data (1992-1994) for Developmental and Reproductive Toxicity Studies using the Crl:CD®(SD)BR Rat - March 1996
• Hematology Parameters for the Crl:CD®BR Rat - February 1993
• Serum Chemistry Parameters for the CRL:CD®BR Rat - February 1993
• Spontaneous Neoplastic Lesions and Selected Non-neoplastic Lesions in the Crl:CD®BR Rat - February 1992
• Spontaneous Ophthalmic Lesions in the Crl:CD®BR Rat - February 1991

Control Data

• Clinical Pathology Data for North American CD® Rat Colonies for January 2006 - December 2011
• Heart Rate for Male CD Rats Fed Purina 5L79 Diet (March 2009)