SCID mice possess a genetic autosomal recessive mutation (scid). Discovered in 1980 by Bosma in C.B-17/Icr mice at Fox Chase Cancer Center. SCID mice show a severe combined immunodeficiency affecting both B and T lymphocytes. They have normal NK cells, macrophages, and granulocytes. To Charles River in 1991 from an Iffa Credo foundation colony.
Tumor biology and xenograft research
Informational Resources: Fox Chase SCID® Mouse
Fox Chase SCID Mouse Health Reports
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We have compiled tumor growth data to assist you in expediting your immunodeficient model selection process.
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Precautionary screening should be performed to confirm that biologics are free of infectious agents and are originating from the appropriate host species.