Origin

The Goto-Kakizaki (GK) rat is a non-obese Wistar substrain which develops Type 2 diabetes mellitus early in life. The model was developed by Goto and Kakizaki at Tohoku University, Sendai, Japan in 1975. To Chugai Pharmaceutical Co. To Charles River Japan in 1995. To Charles River Laboratories in 2006.

Coat Color

White (albino)

Ideal For:

non-obese Type 2 diabetes, mild hyperglycemia, insulin resistant, hyperinsulinemia

Strain Code:

460

Informational Resources: Goto-Kakizaki (GK) Rat

• Animal Models of Metabolic, Renal and Cardiovascular Disease Datasheet

Baseline Colony Data

• Oral Glucose Tolerance Test (OGTT) Values in Female Goto-Kakizaki (GK) and Wistar Rats on Charles River 5L79 Diet (July 2008)

• Oral Glucose Tolerance Test (OGTT) Values in Male Goto-Kakizaki (GK) and Wistar Rats on Charles River 5L79 Diet (July 2008)

• Fed Glucose Values of Female Goto-Kakizaki (GK) Rats on Charles River 5L79 Diet (July 2008)

• Fed Glucose Values of Male Goto-Kakizaki (GK) Rats on Charles River 5L79 Diet (July 2008)

• Weights of Female Goto-Kakizaki (GK Rats) Rats Fed Charles River 5L79 Diet (July 2008)

• Weights of Male Goto-Kakizaki (GK Rats) Rats Fed Charles River 5L79 Diet (July 2008)

• Fed Insulin Levels for Female Goto-Kakizaki Rats on Charles River 5L79 Diet (July 2008)

• Fed Insulin Levels for Male Goto-Kakizaki Rats on Charles River 5L79 Diet (July 2008)

• Fed Cholesterol Values in Goto-Kakizaki Rats on Charles River 5L79 Diet (July 2008)

• Fed Triglyceride Values in Goto-Kakizaki Rats on Charles River 5L79 Diet (July 2008)