The strain was originally developed at the Sloan Kettering Institute where it was backcrossed on a non-specified C57BL/6 strain. The congenic strain "C57BL/6-Ly5.1" carries the allele of the SJL mouse in the Ptprc gene locus: "Ptprca" or "CD45.1" or "Ly5.1". Charles River Europe breeds CD45.1 expressing B6.SJL-Ptprca Pepcb/BoyCrl mice in Italy.
This mouse is primarily used in inflammation and immunological adoptive transfer research.
For more information about Ly5.1 mice, please contact us at firstname.lastname@example.org.
Health Reports for Animal Colonies in Italy
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