Origin

Developed from a line of Crl:CD(SD) rats. Two lines were developed from this outbred colony, the OP-CD (Obese Prone) and OR-CD (Obese Resistant). This model becomes obese when fed high-fat diets. Obesity develops despite having a fully functioning leptin receptor. The control for this model is the Crl:OR(CD).

Coat Color

White (albino)

Ideal For:

obesity, metabolic syndrome
NOTE: This model can be preconditioned on a diet.

Strain Code:

463

Informational Resources: Obese Prone CD (OP-CD) Rat

• Animal Models of Metabolic, Renal and Cardiovascular Disease Datasheet

Baseline Colony Data

• Weight Chart of the Female OP-CD Rat on Various Diets (November 2008)

• Weight Chart for the Male OP-CD Rat on Various Diets (November 2008)

• Weight Chart for Male and Female OP-CD and OR-CD Rats Fed 5L79 Diet (February 2008)

• Weight Chart for Male and Female OP-CD and OR-CD Rats Fed RD12266B Diet (February 2008)

• Weight Chart for Male and Female OP-CD and OR-CD Rats Fed RD12492 Diet (February 2008)

• Comparison of Glucose and Insulin Values in male OP-CD Rats Fed 5L79 Diet (May 2008)

• Comparison of Glucose and Insulin Values in male OP-CD Rats Fed RD12266B Diet (May 2008)

• Comparison of Glucose and Insulin Values in male OP-CD Rats Fed RD12492 Diet (May 2008)