Overview Technical Resources OriginThis model of polycystic kidney disease showing both kidney and liver involvement was identified in a colony of CD rats from the Charles River Japan production facility. The identification of the Pkhd1 gene mutation was reported by Katsuyama and associates in 2000. This autosomal recessive Pkhd1 gene mutation is a model of human autosomal-recessive polycystic kidney disease (ARPKD). To Charles River Laboratories in 2006. Coat ColorWhite (albino) Ideal For:polycystic kidney disease, autosomal recessive trait Strain Code:453 For more information about PCK Rats, please contact us at askcharlesriver@crl.com.
OriginThis model of polycystic kidney disease showing both kidney and liver involvement was identified in a colony of CD rats from the Charles River Japan production facility. The identification of the Pkhd1 gene mutation was reported by Katsuyama and associates in 2000. This autosomal recessive Pkhd1 gene mutation is a model of human autosomal-recessive polycystic kidney disease (ARPKD). To Charles River Laboratories in 2006. Coat ColorWhite (albino) Ideal For:polycystic kidney disease, autosomal recessive trait Strain Code:453