This model was isolated from a C57BL/6NCrl colony in a Charles River Laboratories barrier facility in the US in 2005. The mutation was mapped to a region within less than 2 cM of the leptin receptor on Chr 4. Lack of leptin receptor protein. Het x Het mating.
obesity, hyperinsulinemia, insulin resistance, dyslipidemia, metabolic syndrome, leptin receptor deficiency, fatty liver disease
This model is cryopreserved.
Informational Resources: THE POUND MOUSE
THE POUND MOUSE® is cryopreserved. For more information, contact us at firstname.lastname@example.org.