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Origin

This model was isolated from a C57BL/6NCrl colony in a Charles River Laboratories barrier facility in the US in 2005. The mutation was mapped to a region within less than 2 cM of the leptin receptor on Chr 4. Lack of leptin receptor protein. Het x Het mating.

Coat Color

Black

Ideal For:

obesity, hyperinsulinemia, insulin resistance, dyslipidemia, metabolic syndrome, leptin receptor deficiency, fatty liver disease

Strain Code:

This model is cryopreserved.

Informational Resources: THE POUND MOUSE

Baseline Data

  • Bred In:
  • US