Mouse & Rat Breeding

Charles River provides a full-service rodent colony management program to deliver animals to you when you need them, in the exact quantities you specify, and with the health status that you require.

Our expert staff will work with you to:

  • Develop and execute mouse or rat breeding plans
  • Troubleshoot issues
  • Deliver cohorts of study animals

In addition to providing breeding services, we can help streamline your technicians' workloads while capturing real-time data electronically on each animal. Our Internet Colony Management (ICM™) system complements our breeding services, comprehensively supporting your colonies.

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Available Mouse & Rat Breeding Services
Service Requirements Deliverables Estimated Timeline

Quarantine Services


• Direct animal and environmental samples tested via Mouse Surveillance Plus PRIA™
• Sentinel (immunocompetent and immunodeficient) tested via HM Standard with Helicobacter PCR

4 weeks


12 weeks

Production Breeding & Animal Holding
Hold, breed, age and ship your animals


• Variable based on client needs
• Husbandry, mating, weaning and dedicated project manager supported by Client Portfolio Manager


In Vitro Fertilization (IVF) Colony Expansion
Cut time off your breeding timeline

2–3 homo- or heterozygous males between 12 weeks and 6 months old
*Mice only

• VAF/Elite® mice quantity is based on parameters of the project

15 weeks

MAX-BAX® Speed Congenics
Get a backcrossed colony in half the time

2–3 homo- or heterozygous males between 12 weeks and 6 months old

• All fully congenic mice produced

15 months

Colony Startup Package
Get an established colony quickly

2–3 homo- or heterozygous males between 12 weeks and 6 months old

• Background strain characterization
of 3 mice
• Sperm cryopreservation
• Rederivation
• 24 heterozygous mouse pairs
• PCR genotyping


Mouse Rescue Package

Recovery of a mouse line that is no longer producing offspring

• All animals produced
• Complete health report
VAF/Elite® mice

15 weeks

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Genetic Testing Services

Charles River offers genotyping assays to accurately assess the unique genetics of your lines.

Surgical Services

Charles River can surgically alter your unique animals for use in safety assessment or other lead optimization services.

Discovery Research Services

Charles River offers a host of therapeutic area-based services to provide baseline data on unique animal models.

lab animal technician working with isolators

Additional Resources

This is a collection of resources that further describe our mouse and rat breeding services.