PCR Assays

Charles River offers PCR and RT-PCR detection and quantification methods to detect the presence of bacterial, viral and host cell nucleic acids. PCR is a highly sensitive, reliable and time-efficient method that can also be applied to cell line characterization and viral clearance studies. Most assays offered by Charles River are fully validated, and additional methods are able to be developed and validated upon client request.

Charles River has developed rapid, sensitive and specific broad-range PCR assays to help you to receive your results faster and ensure that you have the information necessary to make decisions in your development and production processes. Our new assays are aimed at detecting the following viruses:

  • Human and canine adenoviruses
  • Human and canine herpesviruses
  • Human and canine papillomaviruses
  • Human polyomaviruses

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Design and execution of a complete testing program for your cell line that is customized to meet your exact specifications and is compliant with international regulatory guidelines.

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We have experience in the development, qualification and validation of in vivo and in vitro viral safety assays along with the design of viral clearance studies for a range of products.

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We work with you to evaluate your quality control (QC) testing programs by reviewing your current testing structure and selecting the best-suited and most cost-efficient mix of insourcing and outsourcing options.