Cell Banking

Charles River has more than 20 years of experience in manufacturing microbial and mammalian working and master cell banks in compliance with cGMP. We typically manufacture more than 100 research and cGMP cell banks annually, and our processes for controlling manufacture have been developed from this large base of experience to ensure a smooth and successful outcome for your manufacturing campaign.

In conjunction with our cell banking and vaccine production services, we offer more than 10 years of experience with long-term storage of clients' banks.


  • All commonly used mammalian cell lines
  • Insect cell lines
  • Avian cell lines
  • Stem cells
  • Aerobic and anaerobic microorganisms


  • Separate, dedicated mammalian and microbial facilities
  • cGMP-compliant environments

Material Storage

  • Materials stored in a cGMP-compliant facility in accordance with sponsor-defined conditions
  • Short- and long-term storage in vapor-phase liquid nitrogen or at -70 °C, as appropriate
  • Segregation to minimize cross-contamination
  • Inventory control system

Sample Monitoring and Security

  • Temperature-mapped storage units maintained in a controlled, limited-access suite
  • 24-hour validated redundancy temperature monitoring system
  • Auxiliary backup generators routinely tested

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