Identification of a compound’s target specificity and potential for off-target effects is a critical step in the drug discovery process and often includes assessments against specific target class families, critical safety targets or by therapeutic area. Charles River offers the largest collection of validated functional assays for ion channel selectivity profiling. Our ion channel portfolio includes over 120 assays, which have been organized into Channel Panels® based on current scientific findings. We can provide functional, manual and automated ion channel screening by therapeutic area for profiling and risk assessment.
Available Channel Panels®