Parkinson's disease is a degenerative disorder of the central nervous system. The motor symptoms of Parkinson's result from the death of dopamine-generating cells in the substantia nigra.
Charles River conducts contract studies in several established animal models of Parkinson's disease to test the efficacy of novel compounds. These models to take into account both acute and symptomatic effects of Parkinson's disease.
Animal Models of Parkinson's Disease
-
6-OHDA Medial Forebrain Bundle Model
-
6-OHDA Striatal Model
-
MPTP Model
-
AAB - Human A53T Transfection Model
-
A53T Alpha-Synuclein Transgenic Model
Testing / Validation Data
Click below to see a sample data set.