Varigenix® Hepatocyte Panels

Charles River, in association with Varigenix®, offers a new tool that has been validated to study the impact of genetic variation in pharmacogenomics and toxicogenomics. Varigenix® hepatocyte panels express genetic variability comparable to human populations and are available as four products. Each hepatocyte panel consists of ~1 million cryopreserved hepatocytes in suspension.

Hepatocyte Panels

The first panel is currently available for purchase and other panels will be produced to meet market demand. 

Panel Strains in addition to parental strains C57BL/6J and DBA/2J
1 Males of 22 BXD strains derived from Taylor series BXD1 to BXD42
2 Females of 22 BXD strains derived from Taylor series BXD1 to BXD42
3 Males of 22 BXD strains derived from BXD43 to BXD103 of the advanced UTHSC series
4 Females of 22 BXD strains derived from BXD43 to BXD103 of the advanced UTHSC series

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Cryopreserved Hepatocytes

Charles River offers rat and mouse hepatocytes to optimize your preclinical resources through early compound differentiation.