Hit Identification

Charles River has a range of orthogonal approaches that can deliver high-quality, validated hit compounds for your drug discovery project. These approaches can be applied in parallel or individually, depending on the nature of the project and the resources available. Our highly experienced teams regularly evaluate early-stage programs and will advise you concerning the best strategy for successful progression to hit-to-lead studies.

Hit Identification Approaches

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3D model of fragment binding with protein

Fragment Screening

Our extensive range of fragment screening technologies allows us to customize a fragment-based lead discovery solution.

High-content Screening

High-throughput screening and high-content profiling using standard cell models, human primary cells or disease-related cell lines.