Non-GLP Toxicology

Charles River provides services in non-GLP bioavailability, pharmacokinetics and toxicity analysis. In addition to in vivo toxicology studies, we provide services to assess the genotoxic and cardiotoxic potential of candidate molecules.

Acute Toxicity Testing

  • Timed dosing and sampling
  • Tissue and/or organ preservation
  • Plasma and/or serum sampling
  • Histology and pathology
  • CBC with differentials

Genotoxicity Testing

  • BlueScreen assay
  • MicroAmes assay

Cardiotoxicity Testing

  • hERG channel blockade

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