Charles River’s structural biology platform supports structure-based drug discovery from gene to final structures, including incorporation of your selected ligands. Our highly experienced staff employ the latest techniques and equipment and have expertise in high-throughput gene expression, automated protein purification and crystallization, and X-ray crystallography. In addition, a range of biophysical techniques is available to accelerate and deepen the understanding of the interactions your ligand makes with its biological target.

Fragment-based Drug Discovery

Extensive capabilities in fragment-based lead discovery including expertise in screening, structural biology, computer-aided drug design and medicinal chemistry. Learn more »

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