By combining proprietary adenoviral technology with complex cellular assays, Charles River’s target discovery group has delivered novel, validated drug targets in a range of therapeutic areas for over 10 years. We examine the effects of introducing shRNAs (SilenceSelect) or full-length cDNAs (FLeXSelect) contained within our libraries of adenoviruses into human primary cells, differentiated stem cells or cell lines. siRNA and miRNA technologies are also available for gene knockdown studies.

Human Primary Cellular Assays - PhenoFocus

A portfolio of over 100 complex human primary cell-based assays for screening in more than 20 different disease area indications. Learn more»

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