Physical Property Measurement

A full knowledge and understanding of the properties of a compound is essential in drug discovery. At Charles River, we can measure a wide variety of molecular properties in both the solid and the solution state to facilitate rapid development.

Physical Properties

  • LogP, pKa, logD
  • Melting points and other thermal events using DSC
  • Degradation using TGA and TGA-IR
  • Hygroscopicity using DVS
  • Particle size
  • Particle morphology using SEM
  • Toughness and hardness
  • Lactose blend performance using NGI technology

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In Vitro ADME Screening

Essential information on potential vulnerabilities of compounds to help direct medicinal chemistry activities.