Diet-Induced Obesity Models

Rodent models chronically fed high-fat diets provide a unique opportunity to assess a compound’s ability to treat obesity and related outcomes in a wide range of manners. Through the use of specific diets, appropriate positive controls and a robust suite of analytical endpoints, researchers can hone in on certain aspects of obesity and related metabolic syndrome endpoints. Be it as simple as a change in body weight gain or as complicated as whole-body calorimetry, body composition, accurate acute food intake and a range of histological markers, our Discovery Services group can accommodate your study design.

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Blog: About Those Obesity Studies…

Joseph Cornicelli, a Scientific Advisor for Charles River Discovery Services in the areas of inflammation, and metabolic and cardiovascular diseases, weighs in on recent data that appear to dampen the health risks of obesity.