Immunology at Charles River is composed of four expertise areas (immunotoxicology/immunomodulation, immunogenicity testing, biomarkers, in vitro assays and molecular biology) which have extensive service offerings to support drug development from discovery and preclinical through clinical sample analysis. We employ over 80 scientists within our dedicated immunology laboratories. Our labs also conduct GLP immunotoxicology assessments in multiple species. Our studies provide you with reports that meet the international regulatory guidelines for biotechnology-derived products (S6) and immunotoxicology (S8 – draft guideline).

At your request, consulting services and clinical strategy assessments are also available.

  • Preclinical and clinical immunology sample analysis
  • Method development and validation
  • Immunotoxicology assessments
    • Immunogenicity
    • Phenotypic responses
    • Immunosuppression
    • Immunostimulation
    • Hypersensitivity
    • Autoimmunity
  • Immunogenicity
  • Immunochemistry
  • Immunopathology and immunohistochemistry
  • Flow cytometry
  • Functional assays
  • Host resistance assays
  • Hypersensitivity testing
  • Autoimmunity
  • Inflammation and disease models
  • Molecular biology assays to assess immune biomarkers
  • In vitro assays 

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