Charles River offers a full range of drug metabolism and pharmacokinetic (DMPK) studies in support of drug candidate selection or regulatory submission. Our skilled ADME scientists, together with our pharmacokineticists, surgeons and bioanalytical chemists, can design and interpret both in vitro and in vivo components of your drug metabolism studies based on your program goals. Our state-of-the-art metabolism and clinical pharmacokinetics laboratories offer fully validated, networked data management systems for radioisotopic, chromatographic and pharmacokinetic evaluations.