Charles River performs a comprehensive array of genomics-based assays to support all phases of drug development, from discovery and preclinical studies through clinical trials, in either singleplex or multiplex formats. Our molecular biology facilities have custom-designed, dedicated laboratories with separate sample processing (nucleic acid extraction), reagent preparation and amplification/product detection areas to minimize the possibility of cross-contamination.
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We isolate and purify DNA and RNA from a variety of tissues, body fluids and cells in culture. Our extraction procedures are optimized to provide the highest quality real-time qPCR results; both quality and yield of extracted nucleic acid samples are assessed prior to being used.