Clinical Pathology

Charles River offers a complete range of clinical pathology laboratory services to support animal models, discovery, preclinical studies and/or clinical trials. Our clinical pathology laboratory staff has extensive knowledge of animal and human hematology, coagulation, clinical biochemistry and urinalysis. In addition, specialized pathology laboratory services are available to meet your development needs for assays/biomarkers for specific research requirements or drug safety studies.

Our staff, including pathologists certified by the American College of Veterinary Pathologists and the European College of Veterinary Clinical Pathology, has expertise across the spectrum of major therapeutic areas and routinely assesses and interprets data from regulatory and investigative/research studies. With six state-of-the-art clinical pathology labs, we can support all stages of the human and veterinary drug development process and conduct research in accordance with the current standards of Good Laboratory Practice (GLP) or Good Clinical Practice (GCP).

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Standard Platforms

  • Hematology and coagulation
  • Clinical biochemistry
  • Urinalysis
  • Bone marrow evaluation

Specialized Platforms

  • Cytology (CSF, BAL, etc.)
  • Hormones
  • Cytokines
  • Platelet function
  • Hemolytic studies
  • In vivo studies
  • Broad experience in regulatory assessment and interpretation of clinical pathology data from regulatory and investigative/research studies
  • Clinical pathology report preparation
  • Scientific cross-linking and integrated reports
  • Bridging of clinical medicine, laboratory medicine and basic sciences
  • Contribution to study design, special investigations, health authorities’ questions and regulatory documents (e.g., expert reports, IBs, CTDs)

You may also be interested in...

Best Practices Article

Check out the article "Best practices for veterinary toxicologic clinical pathology, with emphasis on the pharmaceutical and biotechnology industries" in the September issue of Veterinary Clinical Pathology, with contributions from Charles River clinical pathologists.

Non-GLP Biomarker Services

We can support your drug discovery pipeline by providing biomarker analysis in a non-GxP environment.