Bone Research

Charles River offers a fully integrated service with a team of scientists, pathologists, veterinarians and surgeons in the field of bone research to assess the safety and efficacy of musculoskeletal drugs and devices. Non-GLP efficacy models are also available for your early research. This integrated approach allows the comprehensive evaluation of bone and cartilage drug efficacy, musculoskeletal tissue healing and biocompatibility, orthopedic device efficacy and the effects of new orthobiologic applications.

For our bone research capabilities datasheet and Researcher newsletters, visit the Source℠.

  • Gonadectomy (ovariectomy and orchiectomy)-induced bone loss for osteoporosis drug testing
  • 5/6 nephrectomy model
  • TPTx (thyroparathyroidectomy) model
  • Schenk model in weanling rats (screen for anti-resorptive agents)
  • Bone defect models
  • Orthopedic models
  • Osteoarthritis models
  • Rheumatoid arthritis models

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