Minipigs

minipigDue to an expanding collection of historical control data and wider regulatory acceptance, the minipig continues to build a reputation as a viable alternative large animal model. Charles River has been performing toxicology studies in this species for over 30 years and currently offers minipig toxicology studies at three of our locations in North America and Europe. Our scientists are experienced in performing a wide range of study types in multiple minipig strains (most commonly the Göttingen minipig) as well as full-size domestic swine, and are available to advise on appropriate study design.

We also offer full-service laboratory support to enable each client to have all aspects of a study performed at a single GLP-compliant facility.

For a full description of all study designs and endpoints available for minipigs, download our newest Researcher newsletter, Alternative Nonrodent Models: Minipig Specialty Capabilities, available in the Source℠.

  • Oral (gavage, dietary and water)
  • Intravenous- single bolus or repeat dose
  • Continuous infusion
  • Subcutaneous, intradermal and intramuscular
  • Dermal – open, partial or full occlusion
  • Intranasal
  • Ocular
  • Surgical implant (medical devices)
  • Teratology studies
  • Fertility assessments
  • Juvenile studies
  • Safety pharmacology studies
  • Toxicokinetic (ADME) studies
  • Wound healing studies
  • Diabetic model

You may also be interested in...

Diabetes in the Gottingen Minipig

This webinar will cover methods for obtaining diabetes in the minipig, as well as long-term maintenance of diabetic minipigs and an overview of studies that can be conducted with them.

Rethinking the Minipig

Minipigs have numerous anatomical, physiological, genetic and biochemical similarities to humans, making them ideal models for toxicology testing. Read our Eureka blog, which describes the usefulness of the minipig.

Jacketed External Telemetry Assessment in the Gottingen Minipig

With the RETHINK European FP6 project in mind, the purpose of this study was to determine if jacketed telemetry could be applied to minipig studies for the evaluation of ECGs, as a potential alternative to traditional safety pharmacology studies. (Available in the Source℠)