Making decisions about your safety pharmacology study can be challenging. We can help. Charles River has established ICH core battery tests and supplementary models to meet current regulatory requirements and provide meaningful data. We can customize your study to address both your program- and compound-specific needs, or include our core safety parameters in toxicology studies as an efficient means of meeting regulatory expectations.
Our safety pharmacology facilities feature dedicated telemetry suites, surgical pharmacology capabilities and custom-built cardiovascular laboratories that allow for remote observation of the animals without disrupting data collection.
We have validated the use of electrocardiogram (ECG) pattern recognition software to increase the sensitivity of our ECG analyses, and have integrated automated arrhythmia detection for full ECG data sets.
Visit the Source℠ for more information on our safety pharmacology capabilities.