Efficacy and safety assessments requires blood collection from study animals to gather data on the effects of a drug compound. For bioanalytical evaluation, the microsampling technique refines blood collection and uses a very small amount of blood (typically ≤ 50 µL) to assess whether a drug compound is safe and effective. Consequently, this technique eliminates the need for satellite animals and lessens the level of stress on those animals that have to be used.
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Capillary microsampling has been successfully applied across Charles River in the collection and analysis of large and small molecule bioanalytical samples.