Safety Pharmacology

Charles River has established ICH core battery tests and supplementary safety pharmacology models to meet current regulatory requirements and provide meaningful data to accurately drive your decision-making process.

Our safety pharmacology facilities feature dedicated telemetry suites, surgical capabilities and custom-built cardiovascular laboratories with remote observation of the animals without disrupting data collection. We have validated the use of electrocardiogram (ECG) pattern recognition software to increase the sensitivity of our ECG analyses.

Visit the Source for more information on our safety pharmacology capabilities.

  • Cardiovascular system
  • Respiratory system
  • Central nervous system (CNS)
  • hERG
  • Tier II cardiovascular, CNS and respiratory assessments
  • Renal
  • Gastrointestinal
  • Blood pressure

You may also be interested in...

Central Nervous System

Our wide range of services helps shorten the development cycle of compounds with neurological implications.

Respiratory Disease

Our expert scientists provide a wide range of capabilities to support your development program from discovery to safety testing.

Cardiovascular

We recognize that cardiovascular drug development programs are complex and often require multidisciplinary research.