Charles River offers a wide range of services supported by our scientific depth, unique technical capabilities and experience in all the major neurodegenerative diseases and neurological indications, such as schizophrenia, Alzheimer’s disease, Parkinson’s disease, chronic pain, epilepsy, multiple sclerosis, stroke and ischemia. From animal models of disease to discovery research and preclinical testing, we have developed tools to assist clients in identifying the most promising candidate and shortening the development cycle of potential therapies with neurological implications. Basic Research PGP (P-glycoprotein Deficient) Mice NSE-p25 Mice Surgically Altered Models Operations and Staffing Support Drug Discovery In Vivo Pharmacology Studies In Vitro Pharmacology Studies Imaging Services Behavioral and Cognitive Tests Discovery Pathology Immunology Biomarker and Analytical Services Safety Assessment Neurotoxicity Testing Neurobehavioral Screening Neuropathology Ocular Toxicology Clinical Support Clinical Bioanalysis Clinical Pharmacokinetics Clinical Immunology and Biomarker Services Pathology for Clinical Trials Manufacturing Support GMP-Compliant Biopharmaceutical Manufacturing Endotoxin Detection and Microbial Identification