A position of responsibility
Bringing and sustaining vital drugs to market safely, and as quickly as possible.
20,000+
Employees working across 100+ facilities in over 20 countries
100%
Renewable electricity expected globally by 2030
See how our purpose-driven Environmental, Social and Governance (ESG) strategies empower and drive us.
4,000+
Employees in 11 dedicated global resource groups (18% of our employees), helping to foster diversity, equity, inclusion and belonging.
53%
Women representation as managers and 42% of our executive leaders (VP+) are women – globally
Learn about our commitment to creating a workplace where everyone can succeed and thrive, and how it enables us to deliver the highest quality each day.
$200M
Invested over the past four years, as part of our strategic partnership strategy to develop alternative method advancements
70+
Years of innovation in responsibly advancing replacement, reduction, and refinement in animal research.
See how responsible and innovative advancements in science and technology enable us to drive change in the way we discover and develop drugs and therapies.
80%
Of the FDA-approved drugs over the past five years were worked on by Charles River
1,500
IND studies supported in the last 12 months
Listen to the stories behind the bold science from those developing and receiving life-changing therapies.
This is Your Moment
Our people are the heart of our organization. Their passion and skills are critical to our success and achieving our purpose of creating healthier lives. We strive to create a culture of inclusion, continuous learning, and wellbeing for our people from day one.
Events and Training
Jun 20, 2024| Durham, NC | Conference
PDA Southeast Spring Conference
Jun 25 - 27, 2024 | Munich, Germany | Conference
European Microbiology Conference & Pre-Conference Workshop
Jun 26 - 27, 2024 | Strasbourg, France | Conference
A3P Microbiology Conference
Jun 26 - 27, 2024 | Amsterdam, The Netherlands | Conference
PDA Virus Conference 2024
Sep 10 - 11, 2024 | Philadelphia, PA | Symposium
8th Annual Viral Safety and Viral Clearance Summit
Supporting the full drug discovery and development continuum
No matter where you are in your drug development journey, we can provide you with a wide range of products, models, services and guidance that are tailored to your specific needs.
Basic Research
Basic research is the foundation of all scientific breakthroughs, improving our understanding of biology and advancing our knowledge of the life sciences. From an expansive selection of research animal models and human-derived products to the management of genetically modified models and health surveillance, your next breakthrough starts here.
Support your basic research with help from the leading global supplier of laboratory animal models and services.
The leading developers of cutting-edge cell therapies and basic research trust us as their cell sourcing provider.
Genetically Engineered Animal Models and Services (GEMS) team helps you select, customize, and maintain the right mice for your research. Services for genetically engineered animals include mouse and rat model creation, breeding, genotyping, and mouse embryo and sperm cryopreservation.
Discovery
Drug discovery is a challenging journey. Too often, a novel compound’s road to market is delayed – or blocked entirely – by limited resources or expertise. With a comprehensive multi-modality discovery service portfolio and a staff of hundreds of scientists, we have the scientific excellence and technological capabilities to support our clients throughout the drug development life cycle.
Reduce time to clinic by up to a year with an integrated drug discovery approach in which target discovery, hit id, hit-to-lead, lead optimization, safety, and toxicology are all managed by the same project team.
In vitro to in vivo translation is difficult, costly, and often fails. Advance your discovery research with our translationally focused approach across a range of therapeutic areas including oncology, neuroscience, and immunology.
Antibody discovery services designed with your IND in mind. Comprehensive solutions, tailored to your unique vision for your next antibody therapeutic.
Preclinical Testing
Determining a drug’s safety profile is perhaps one of the most critical stages of the drug development pathway. Complications and inefficiencies with preclinical studies can create costly delays. Using state-of-the-art technologies in a global network of facilities, our skilled scientists execute individual studies and custom testing programs that are designed with a client’s goals in mind.
Two primary study offerings are available for non-GLP toxicology studies for lead optimization and preclinical development.
Successfully initiate and complete your IND-enabling program while meeting regulatory expectations with our unique range of IND-enabling studies.
Our carcinogenicity studies include expert support in project design, model selection, and in vivo and ex vivo data for final submission.
Our tailored global testing and manufacturing services support clients throughout the biologic development cycle, from discovery through preclinical and clinical studies to marketed product release.
Accelerate the development of your biopharmaceutical from concept to cure with our CGMP compliant biologics contract manufacturing services.
A flexible testing platform that can be deployed where and when you need it, whether it’s located at your facility, one of our satellite labs, or even within the walls of the many Charles River facilities itself.
Manufacturing and Commercialization
Our development, manufacturing, and testing support services enable our clients to produce safe and compliant products. Our scientists, technicians, and expert support teams can provide the insight, advice, and tools needed to streamline the manufacture and release of safe products for patients in need.
Fastrack your cell and gene development and manufacturing with our end-to-end scalable solutions from early stage-research and testing through commercial release.
Navigate seamlessly throughout the biologic development cycle, from early concept to market-ready with our tailored, CGMP global testing and manufacturing solutions.
Elevate your contamination control strategy and accelerate production with confidence. Our rapid, accurate, and compliant microbial testing solutions optimize your QC workflow.
Scientific and Regulatory Guidance
Navigating the changing regulatory landscape is an ongoing challenge for many involved in the development, approval, and manufacture of pharmaceuticals and medical devices. We've built a unique global team of scientific advisors whose expertise spans various drug modalities, therapeutic areas, and key stages in the drug development process.
One Step by Charles River is a comprehensive, tailored suite of CRO drug discovery and development services in target discovery, lead optimization, development chemistry, GMP, drug product development and CMC strategy.
Expedite your investigational new drug (IND) application with Fast Lane Paradigm. Learn how to reduce white space between studies and accelerate time to clinic for you INDs.
Charles River can conduct an investigational new drug (IND) study from start to finish, and offers stand-alone studies needed for IND-enabling submissions. Our IND experts have expertise in all major therapeutic areas, including medical devices and gene and cell therapies.