2021 SOT Virtual Event Poster Presentations
Wednesday, March 17 | 11:15 AM – 1:00 PM
| P105: Development of a Strategy to Determine the In Vitro Induction of T4-Glucuronidation in Rat and Human Jelle Reinen, Maarten Smit, Betina Elemark, Mira Wenker |
Thursday, March 18 | 11:15 AM – 1:00 PM
| P145: Evaluation of Drug Displacement from Melanin as a Screening Method for Retinal Toxicity Adrian Sheldon, Patty Walton, Sarah Meloche, Karen Stams, CO-AUTHORED WITH BIOGEN |
| P147: A 1-Month Toxicology and Biodistribution NHP Pilot Study Evaluating a Single Subretinal Bilateral Administration of SPVN06 - A Novel AAV-based Gene Therapy for Treatment of Rod-Cone Dystrophies Agnostic of the Causative Mutation Thomas Vihtelic, Ryan Boyd, Lauren Knupp, co-authored with Institut de la Vision, University of Pittsburgh |
Tuesday, March 23 | 11:15 AM – 1:00 PM
| P129: Implementation of an In Vitro FTC-238-hr TPO-based Tyrosine Iodination Method to Evaluate Chemicals for Thyroperoxidase (TPO)-Inhibiting Properties Jeroen Rijk, Ester de Laat, Gijs van Slobbe, Jan Toersche, Mira Wenker CO-AUTHORED WITH EU Commission Joint Research Centre, and US FDA/NCTR |
| P206: A New 90-day Drinking Water Study of Sodium Cyanide in Rats to Further Evaluate NTP Findings and Inform Risk Assessment Melinda Tyner, Pragati Coder |
| P275: A GLP Validation of the 3D Skin Comet Assay Using Phenion Full-Thickness Skin Models: An Alternative to Animal Testing Thalita Zanoni, Annie Hamel |
| P276: Application of Liver-on-Chip Integrated with Human Lymphobastoid Cells (TK6) to Genotoxicity Testing: Go with the Flow and Reduce Animal Testing Annie Hamel, Deborah Lenart, Ammer Khawam, Karen Di Perna, Thalita Zanoni |
| P294: Next Generation Risk Assessment Approach for Inhalation: Polymer Case Studies J. Wallace, co-authored with Unilever and IIVS and Epithelix |
Wednesday, March 24 | 11:15 AM – 1:00 PM
| P156: Optimization of Extraction Method B Using Common Organic Solvents for Dosing in Genotoxicity In Vitro Assays Farida Merah |
| P174: Comparison of Immunoconditioning Regimens for Cell Therapy Toxicology Studies Using the NCG or NSG Mouse Models Robert Tavcar, Cristina Ballersteros, Christian Li., Selly Hung, Karen Wong, Simon Authier |
| P167: Retrospective Analysis on the Tolerability of Commonly Used Vehicles in Nonclinical Studies Coralie Perret, Claire Tardiveau, Nathalie Truchot-Limonne, Laure Penard, and Stephane Baudet |
Thursday, March 25 | 11:15 AM – 1:00 PM
| P102: Development of Rat Models of Acute Respiratory Distress Syndrome (ARDS) for Efficacy and Safety Assessment Mary McElroy, James Punton, Angela Marsden, Pan Fillis, Kristen Maclellan, James Baily, Aileen Milne |
| P109: Enhancing the Environment for Rodents in Toxicology Studies Emmanuel Boulay, Robert Tavcar, Christian Li, Elizabeth Lambert, Julie Roy, Marika Arsenault, Simon Authier |
| P171: Seizure Assessments in Preclinical Species: Review of Data Analysis Strategies Simon Authier, Michael Accardi, Robert Tavcar, Phoebe Zhong, LoΪs Miraucourt, Jerneja Stare, Christian Li, and Erik Larson |
| P165: Differences in Spontaneous Neoplastic Incidence in Crl:CD(SD) Rats and Crl:WI(Han) Rats Mark Morse, Christopher Papagiannis, Don Stump |
| P166: Reproducibility of Survival and Spontaneous and NMU-Induced Neoplastic Incidence in CByB6F1-Tg(HRAS)2Jic (Tg.rasH2) Mice over the Last Decade John Ciallella, Kimberly Bonnette, Mark Morse |