Hagen Klett graduated from the University of Freiburg with a Master of Physics degree focusing on mathematical modeling of life science processes. He then continued with a PhD in bioinformatics at the German Cancer Research Center, gaining expertise in oncology research, various bioinformatic tools, and the handling of high-throughput data. He later joined Charles River as a scientist in charge of the molecular characterization of tumor models for clinical testing, bioinformatics projects, and internal R&D.
- Induction of Acquired Resistance towards EGFR Inhibitor Gefitinib in a Patient-Derived Xenograft Model of Non-Small Cell Lung Cancer and Subsequent Molecular Characterization (Cells)
- Identification and Validation of a Diagnostic and Prognostic Multi-Gene Biomarker Panel for Pancreatic Ductal Adenocarcinoma (fronteirs in genetics)
- Smoking is associated with hypermethylation of the APC 1A promoter in colorectal cancer: the ColoCare Study (The Journaly of Pathology)
- Differences in DNA Methylation and Functional Expression in Lactase Persistent and Non-persistent Individuals (Nature)
- Robust prediction of gene regulation in colorectal cancer tissues from DNA methylation profiles (Journal Epigenetics)
- Delineating the Dynamic Transcriptome Response of mRNA and microRNA during Zebrafish Heart Regeneration (Biomolecues)