After graduating from the University of Naples (Italy) with a degree in medical biotechnology, Mariangela went on to earn her PhD in molecular and cellular biology in a joint program between Merck, University of Perugia (Italy) and University of Cambridge (UK). As a graduate student, she studied the mechanism of action of a small molecule compound used to reprogram somatic cells to stem cells progenitor cells. While at the University of Cambridge, she earned an MS in medical sciences and completed a postdoctoral fellowship in the Clinical Neuroscience department, where she gained extensive experience with stem cell differentiation models in the context of neurodegenerative diseases.
Mariangela joined Charles River in 2013 and she is currently a group leader in the biology department where she has established stem cell platforms in support of drug discovery programs.
- Depopulation of α-synuclein aggregates is associated with rescue of dopamine neuron dysfunction and death in a new Parkinson’s disease model (Acta Neuropathologica)
- Depopulation of dense α-synuclein aggregates is associated with rescue of dopamine neuron dysfunction and death in a new Parkinson’s disease model (Acta Neuropathologica)