Dr. Khot is passionate about developing microbial diagnostics to improve product quality and patient care. He has successfully led numerous projects to evaluate, develop, validate, and implement microbial diagnostic assays in regulated environments. As the R&D Manager for Accugenix®, he is responsible for establishing strategies for executing scientific research and technical stages of product development. His interests include microbial detection, identification, and susceptibility, strain typing, antimicrobial resistance, phylogenetics, biofilms, mass spectrometry, nucleic acid extraction and amplification, Sanger sequencing, next-generation sequencing, metagenomics, spectroscopy, cell viability indicators, multivariate statistics, and machine learning.
Dr. Khot earned his PhD from the University of Utah and completed a postdoctoral fellowship in molecular diagnostics of infectious diseases at the Fred Hutchinson Cancer Research Center, Seattle. Before joining Charles River, he worked as a research scientist in the Clinical Microbiology Division at ARUP Laboratories, Salt Lake City (a national clinical and anatomic pathology reference laboratory).
Articles & Publications
- Identification of Filamentous Fungi with MALDI-TOF Mass Spectrometry (PDA Poster)
- Operational impact of library development on the identification of organisms in the family Bacillaceae (PDA Poster)
- Data Interpretation criteria for MALDI-TOF Mass Spectrometry (PDA Poster)
- A caveat to identifying QC strains (Eureka Blog)
- Optimization of MALDI Mass Spectrometry Analysis for Bacterial Identification (J Clin Microbiol. publication)
- PCR-based diagnosis of human fungal infections (Expert Rev Anti Infect Ther. publication)
- Candida albicans Biofilms Resistance to Amphotericin B (Antimicrob Agents Chemother. publication)