Serotonin (5-hydroxytryptamine, 5-HT) exerts its many physiological effects through 13 distinct receptor subtypes in humans. These subtypes fall into seven structurally-defined classes (5HT1 to 5HT7). Among them, 5-HT1A receptors are expressed mainly in the CNS system where they induce neuronal inhibition and controls behaviour, such as sleep, food intake, thermoregulation, aggression, and anxiety. This receptor has been used as a target for developing drugs to treat anxiety and depression.
Human 5-HT1A Serotonin Receptor Membranes
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