Human Cav1.2/β2/α2δ1 Calcium Channel Cell Line

The human CACNA1C gene encodes the pore-forming subunits of Cav1.2. CACNB2 and CACNA2D1 encode auxiliary subunits that modulate gating and pharmacological properties. Cav1.2 channels expressed in heart, smooth muscle, neurons, and endocrine tissue are therapeutic targets in cardiac arrhythmia and hypertension.

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