The CB2 cannabinoid receptor is expressed primarily in cells of the peripheral immune system and is a target for cannabinoids (Munro et al., 1993; Gerard et al., 1991), the psychoactive ingredients of marijuana. Other members of the cannabinoid family of receptors include the CB1 cannabinoid receptor, which is expressed primarily in brain, and GPR55 (Ryberg, 2007). When activated, the CB2 receptor inhibits adenylate cyclase by coupling through Gi.
Human CB2 Cannabinoid Membranes
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