The human GABRA1, GABRB2, and GABRG2 genes encode the Cl--selective, ionotropic GABAA receptor-channel. Mutations in GABRA1 have been linked to familial juvenile myoclonic epilepsy. GABAA receptors expressed in CNS neurons are therapeutic targets in treatment seizure and anxiety.
Human GABAA (α1/β2/γ2) Receptor Cell Line
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