GPR43 is a member of the free fatty acid G protein-coupled receptor family and is activated by short-chain fatty acids (SCFAs). Expression analysis shows that GPR43 is expressed selectively in leukocytes and to a lesser extent, in spleen. Upon activation by propionate or acetate, GPR43 has been shown to mobilize intracellular calcium in both recombinant systems as well as in human granulocytes.
Human GPR43 Free Fatty Acid Receptor Cell Line
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