Human Kir3.1/Kir3.4 Potassium Channel Cell Line

The human KCNJ3 and KCNJ5 genes encode the pore-forming subunits of heteromeric Kir3.1/Kir3.4, an inward rectifier potassium channel. Kir3.1/Kir3.4 channels expressed in heart are linked to M2 muscarinic acetylcholine receptors that mediate vagal inhibitory control of heart rate. Kir3.1/Kir3.4 is a potential target for treatment of atrial fibrillation.

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