The human KCNJ11 gene encodes the pore-forming subunit of heteromeric Kir6.2/SUR2A, an ATP-sensitive, inwardly rectifyiing potassium channel. ABCC9 encodes the SUR2A subunit which confers sulfonylurea sensitivity. Kir6.2/SUR2A channels expressed in heart are therapeutic targets for cardiac ischemia.
Human Kir6.2/SUR2A Potassium Channel Cell Line
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