The human KCNA5 gene encodes the pore-forming subunit of Kv1.5, a voltage-gated potassium channel. A KCNA5 mutation has been linked to an inherited form of atrial fibrillation. Kv1.5 channels are widely expressed in heart, colon, kidney, vascular smooth muscle and CNS, and are therapeutic targets in atrial fibrillation, pulmonary hypertension, cancer, and multiple sclerosis.
Human Kv1.5 Potassium Channel Cell Line
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