The human KCNQ1 gene encodes the pore-forming subunit of Kv7.1, a voltage-gated potassium channel. KCNE1 encodes an auxiliary subunit that modulates gating and pharmacological characteristics. Kv7.1/KCNE1 channels expressed in heart are safety targets in cardiac long-QT risk assessment.
Human Kv7.1/KCNE1 Potassium Channel Cell Line
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