Human M2 Muscarinic Receptor Membranes

The five muscarinic receptor subtypes all mediate the action of acetylcholine. The odd-numbered receptors (m1, m3, and m5) couple efficiently through Gq/11 to activate phospholipase C and lead to elevation of intracellular calcium, whereas the even-numbered receptors (m2, m4) are efficiently coupled to Gi and lead to inhibition of intracellular cAMP along with several other signal transduction pathways.

Catalog Number


Related Cell Lines

For pricing information, detailed technical sheets, or to speak with one of our experts, please contact us at 1.877.CRIVER.1 (1.877.274.8371) or by using our online form.

Can't find what you are looking for? Contact us. We are always developing new cell lines and can work with you on custom projects.

View All Cell Lines