The human P2RX3 gene encodes P2X3, an ionotropic ATP receptor that functions as an ATP-activated cation channel expressed in spinal cord and sensory neurons. P2X3 receptors are therapeutic targets in treatment of neuropathic and inflammatory pain, inflammatory bowel disease, urinary incontinence, and cough.
Human P2X3 Purinergic Receptor EZCells™ TT
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